Assay
Age
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Immunohistochemistry (whole mount)
3 DPC
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Sox2 SRY (sex determining region Y)-box 2 (Synonyms: lcc, Sox-2, ysb) | |
Results | Reference |
1* | J:81180 Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R, Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 2003 Jan 1;17(1):126-40 |
1* | J:284140 Frum T, Watts JL, Ralston A, TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage. Development. 2019 Sep 6;146(17):dev179861 |
1 | J:344071 Li L, Lai F, Hu X, Liu B, Lu X, Lin Z, Liu L, Xiang Y, Frum T, Halbisen MA, Chen F, Fan Q, Ralston A, Xie W, Multifaceted SOX2-chromatin interaction underpins pluripotency progression in early embryos. Science. 2023 Dec 15;382(6676):eadi5516 |
1* | J:314924 Liu Y, Sun J, Su Y, Lin J, Lv C, Mo K, Xu S, Wang S, Nuclear-localized eukaryotic translation initiation factor 1A is involved in mouse preimplantation embryo development. J Mol Histol. 2021 Oct;52(5):965-973 |
1* | J:326575 Tsume-Kajioka M, Kimura-Yoshida C, Mochida K, Ueda Y, Matsuo I, BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos. BMC Biol. 2022 Mar 9;20(1):64 |
1 | J:228855 Wicklow E, Blij S, Frum T, Hirate Y, Lang RA, Sasaki H, Ralston A, HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. PLoS Genet. 2014 Oct;10(10):e1004618 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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